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Now, this doesn’t necessarily mean that lower omega-3 levels cause cognitive impairment.
That comes out to be about a teaspoon less brain matter.
Higher EPA and DHA levels correlated with larger brain volume eight years later.
While normal aging results in overall brain shrinkage, having lower long-chain omega-3s may signal increased risk.
Since the level of DHA in the brain tends to correlate with the level of DHA in the blood, one can do cross-sectional studies of dementia and pre-dementia patients, and they do tend to have lower levels of both long-chain omega-3s EPA and DHA circulating in their bloodstream.
Lower levels of the long-chain omega-3 fat DHA in some areas of Alzheimer’s brains got people thinking that maybe DHA was protective.