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Increased heart rate, sedation, irritability, dizziness, and decreased coordination can also occur.

Men with prostate enlargement who take trazodone may be especially likely to have problems with urinary retention.Before starting treatment, people with these conditions should discuss the relative risks and benefits of treatment with their doctors to help determine if protriptyline is the right antidepressant for them.Trazodone may increase heart rate and stress on the heart.It may be dangerous for people with cardiovascular disease, especially those who have recently had a heart attack, to take this drug.In rare cases where patients with cardiovascular disease must take trazodone, they should be monitored closely for cardiac rhythm disturbances and signs of cardiac stress or damage.

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